EU Joint Programme – Neurodegenerative Disease Research (JPND)


JPND (EU Joint Programme – Neurodegenerative Disease Research) is the largest global research initiative aimed at tackling the challenge of neurodegenerative diseases. JPND aims to increase coordinated investment between participating countries in research aimed at finding causes, developing cures, and identifying appropriate ways to care for those with neurodegenerative diseases.

The neurodegenerative diseases that JPND focuses on are the following:

  • Alzheimer’s disease (AD) and other dementias
  • Parkinson’s disease (PD) and PD-related disorders
  • Prion disease
  • Motor neurone diseases (MND)
  • Huntington’s Disease (HD)
  • Spinocerebellar ataxia (SCA)
  • Spinal muscular atrophy (SMA)

Among a wide range of actions in different areas related to neurodegenerative diseases, the instruments with which JPND carries out its research strategy agenda include calls for research projects that address the agenda’s thematic priorities. Up to date the NCN together with JPND network announced two calls for proposals on Neurodegenerative Diseases.

Calls for proposals

European research projects for cross-disease analysis of pathways related to Neurodegenerative Diseases (closed)

There is clinical, genetic and biochemical evidence that similar molecular pathways are relevant in different neurodegenerative and other chronic diseases. Therefore, clinical phenotypes alone seem insufficient to provide an understanding of the underlying mechanisms involved, and to be the sole basis for prognosis and diagnosis of neurodegenerative diseases. 

The aim of the call is to establish a limited number of ambitious, innovative, multi-national and multi-disciplinary collaborative research projects that:

  • combine experimental approaches from fundamental, pre-clinical and/or clinical with computational approaches
  • perform network analyses in different neurodegenerative and other chronic diseases to elucidate the underlying mechanisms common and differing in the investigated diseases
  • will add value to existing research by analysing diseases across traditional clinical boundaries, thereby gaining deeper understanding of the patho-physiological mechanisms of the diseases.

The following neurodegenerative diseases are included in the call:

  • Alzheimer’s disease and other dementias
  • Parkinson’s disease and PD-related disorders
  • Prion disease
  • Motor neuron diseases
  • Huntington’s disease         
  • Spinocerebellar ataxia (SCA)
  • Spinal muscular atrophy (SMA).

Research team: composed of research a minimum of 3 and a maximum of 6 groups of researchers from countries participating in this call

Countries participating in the call:

Belgium, Canada, Finland, France, Germany, Ireland, Italy, Luxembourg, the Netherlands, Norway, Poland, Portugal, Slovakia, Spain, Sweden, Turkey

Project duration: up to 3 years

NCN budget for the call: € 300 000

Timeframe:

Pre-proposal application deadline: 18th of February 2014

Full-proposal application deadline: 23rd of June 2014

Final results: October 2014                  

Call documents:

Call text: http://www.neurodegenerationresearch.eu/fileadmin/Documents/2013/Call_Documents/2013_Calls/Cross_Disease_Analysis/JPND_call_Text_CD_final.pdf

Country-specific details: http://www.neurodegenerationresearch.eu/initiatives/annual-calls-for-proposals/closed-calls/cross-disease-analysis-2013/country-specific-details/

FAQ: http://www.neurodegenerationresearch.eu/?id=232

For more information please click here: http://www.neurodegenerationresearch.eu/?id=300   

Polish project awarded within the call:

Identification and structural characterization of the primordial cytotoxic conformers of the amyloidogenic cascade: Ideal prevention/diagnostic/therapeutic targets in neurodegeneration

Polish PI:

  • prof. Marek Cieplak, Institue of Physice, Polish Academy of Sciences

Partners:

  • dr Mariano Carrión-Vázquez – Proejct Leader, (CSIC, Spain),
  • dr Damien Thompson (University of Limerick, Ireland)

The identification of genetic, epigenetic and environmental risk and protective factors for Neurodegenerative Diseases (closed)

It is widely perceived that a lack of knowledge regarding the causes of specific neurodegenerative diseases is one of the greatest unmet needs to be adDressed in ND research. Therefore, it is of utmost importance to better understand:

  • the genetic, epigenetic and environmental factors that underlie an individual’s risk and resilience
  • the triggering events leading to illness
  • the relationship and interplay between these factors and their relative importance
  • the role of potential environmental and behavioural modulators.

Research team: composed of research teams from at least 3 countries participating in the call

Countries participating in the call:

Austria, Belgium, Denmark, Finland, France, Germany, Israel, Italy, Luxembourg, the Netherlands, Norway, Poland, Portugal, Slovakia, Spain, Sweden, Switzerland, Turkey, United Kingdom

Project duration: up to 3 years

NCN budget for the call: € 500 000

Timeframe:

Application deadline: 19th of March 2013

Final results: June 2013                  

Call documents:

National eligibility criteria

Call text                                                   

Frequently asked questions


Contact

Dr Malwina Gębalska, tel: 00 48 519 404 997